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Harry Hollingworth, a young Barnard College professor, conducted pioneering psychopharmacology research in 1911 into the effects of a food additive, caffeine, on behalf of the Coca-Cola Company, which was being sued by the federal government for adding an injurious ingredient to a food. 

Hollingworth found no deleterious effects of caffeine, but the lawsuit known as the “United States v. Forty Barrels and Twenty Kegs of Coca-Cola” was dismissed on a technicality.  Before agreeing to do the research, Hollingworth insisted that that his experiments were to be double-blind and that he was to be free to publish the results, whatever they were.


US v Forty Barrels and Twenty Kegs of Coca Cola